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    *Posttraumatic stress disorder (PTSD) refers to the collection of re-experiencing, avoidance, and hyperarousal symptoms that persist for more than one month after exposure to a traumatic event. Sleep disturbances including nightmares and insomnia characterize PTSD.

    *Sleep disturbances are often resistant to first-line treatments of PTSD

    *This study uses two treatment arms, a medical, and a behavioral. Prazosin, an alpha-1 antagonist, is a promising pharmacological strategy for reducing nightmares and insomnia. Also, preliminary data suggest that an evidence-based behavioral intervention aimed at reducing sleep disruption, increasing sleep consolidation, and reducing nightmares can also be efficacious.
     
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  • National Center for PTSD
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